Preventing type 1 diabetes in childhood

Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing ? cells of pancreas are destroyed by T lymphocytes. Recent studies have demonstrated that monitoring for pancreatic islet autoantibodies, combined with genetic risk assessment, can identify most children who will develop T1D when they still sufficient cell function to control glucose concentrations without need insulin. In addition, there has been recent success secondary prevention using immunotherapy delay progression preclinical disease, and primary approaches inhibiting initiating process entered large-scale clinical trials. By changing focus management from late diagnosis insulin replacement early preservation, we anticipate a future daily injections T1D.